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Due to its relatively brief course of treatment, written exposure therapy may be a more efficient method in reducing PTSD symptoms among U.S. military members, according to a randomized clinical trial published in JAMA Network Open.

Military veterans may be at elevated risk for COVID-19–associated psychiatric issues given high rates of preexisting psychiatric conditions, such as posttraumatic stress disorder (PTSD) and suicidal ideation (SI). In this survey study, we analyzed data from a national sample of US military veterans to examine (1) the prevalence of COVID-19–associated PTG among veterans with and without COVID-19–associated PTSD symptoms and (2) the incremental association between PTG and SI during the pandemic.

Post-traumatic stress disorder (PTSD) is a major problem among military veterans and civilians alike, yet its pathophysiology remains poorly understood. We performed a genome-wide association study and bioinformatic analyses, which included 146,660 European Americans and 19,983 African Americans in the US Million Veteran Program, to identify genetic risk factors relevant to intrusive reexperiencing of trauma, which is the most characteristic symptom cluster of PTSD. In European Americans, eight distinct significant regions were identified. Three regions had values of P < 5 × 10⁻¹⁰: CAMKV; chromosome 17 closest to KANSL1, but within a large high linkage disequilibrium region that also includes CRHR1; and TCF4. Associations were enriched with respect to the transcriptomic profiles of striatal medium spiny neurons. No significant associations were observed in the African American cohort of the sample. Results in European Americans were replicated in the UK Biobank data. These results provide new insights into the biology of PTSD in a well-powered genome-wide association study.

In this cohort study of more than 350 000 veterans, even mild TBI without LOC was associated with more than a 2-fold increase in the risk of dementia diagnosis.

First study to compare neurological and ocular effects of blast injury may open up paths to new interventions.

A new study reveals previously undetected change patterns in the brains of eight veterans, all exposed to blasts from high explosives in combat.

Many military personnel who experience blast-related traumatic brain injury (MTBI) have lasting brain damage as seen by MRI, according to a study published in Radiology.

Studies show that binge drinking after a TBI, especially for active duty and veterans, could be a significant risk