The Connection Between TBI and Neurodegenerative Diseases

What's the differences between traumatic brain injury and neurodegenerative diseases?

See more videos with Dr. Jeffrey Bazarian.

There is a connection between traumatic brain injury and neurodegenerative diseases like Alzheimer's and Parkinson's. We've seen this in observational studies. People kind of want to know what that link is. Is it a strong link, or is it just an observational thing? Can we do this in the laboratory to an animal? Can we hit a mouse and then show that it develops Alzheimer's? So, there is a good deal of work trying to establish that link and find out what it is about the brain injury that predisposes someone then to neurodegeneration. And this has really been in the public eye since several football players who had well-documented concussions, then died at an early age and donated their brains such that they could be autopsied. Scientists were able to see that they had signs of Alzheimer's at fairly early ages. We're talking about 40 years old, 50 years old-- way, way, way before most people develop Alzheimer's.
Posted on BrainLine April 1, 2009.

Comments (2)

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I hit a semi head on and was in a coma. 5 yrs later I have so many memory problems. Not sure what day it is, can't remember where I placed keys,  miss appointments, hard to tell how long ago i did something. I cry a lot, do not remember wreck and can only recall very little of the hospital stay. Words are hard to fiind when I talk and sometimes I tell someone something more than once forgetting I already told them. What does all this mean?

Hubby had a TBI 40 yrs ago - car wreck w/small stroke, in a coma for 3 wks. He had a much less dire car wreck 2 yrs ago, and I began seeing cognitive declines enough to look into.
No one can validate that his brain is slowly losing function again.
1. Is there any hope to be had for him?!?

2. Can I find any support groups for me in Chgo area (he's not interested)?


Shy Wife