A brief summary of current research.
Müller, K, Ingebrigtsen, T, Wilsgaard, T, Wikran, G, Fagerheim, T, Romner, B, Waterloo, K Neurosurgery: April 2009 — Volume 64 (4), pp 698-704.
This study looked at several types of medical assessments to determine which might have an ability to predict problems six months after a mild brain injury. Using neuropsychological testing to assess cognitive skills, investigators found the following:
- CT scans or MRIs that showed TBI, a Glasgow Coma Scale score of <15, and a specific elevated protein (serum S100-B) all predicted impaired cognitive performance at baseline and at six months; the genetic marker apolipoprotein (APOE) did not.
- There was significant improvement in performance six months after the mild brain injury.
- Having the APOE gene was significant for predicting less improvement at six months.